Expert driven research for medical innovation Oxford Cardiomox Technology
Strong scientific expertise
Working with pioneering researchers, who have played a key role in developing MCG for clinical applications in the last 20 years, Cardiomox has a strong technical and scientific background. In 2013, Sosnytskyy et al., showed that MCG allowed a clear distinction with high specificity and high sensitivity between healthy patients, subjects with either myocarditis or with ischemic heart disease, making it a powerful diagnostic tool for heart conditions. A strong understanding of the technology and its underpinning scientific advances are key to the development of effective medical innovations. As a result the MCG-9 from Cardiomox combines effective shielding, field compensation and gradiometric pick up for highly sensitive and accurate measurements.
Device safety : no shielding required
Cardiomox’s MCG-9 does not require a shielded room as the SQUID is shielded against magnetic and radio-frequency fluctuations through a combination of room temperature and super conductive foils. Fluctuations in magnetic field induce currents in the foils that generate a counter magnetic field. Through the careful alignment of these foils background noise is suppressed allowing the detection of the signals arising only from the patient.
Accuracy achieved through field compensation
The device has 9 SQUID sensors used to measure the signals from the patient plus a further 27 coils that measure background variations in the magnetic field in three dimensions. The signals arising from these can be scaled and subtracted from the measured signal allowing Cardiomox’s MCG-9 to detect only the fluctuations in magnetic field arising from the patient.
Increased sensitivity with gradiometric pick-up
To ensure only local signals are detected the Cardiomox MCG-9 device makes use of a gradiometer. Whilst more remote sources of magnetic field give rise to homogeneous fields, those close to the SQUID exhibit stronger fluctuations in field. The gradiometer allows the device to subtract any large homogeneous fluctuations further enhancing the sensitivity of the instrument.